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Longevity·SmartPeptide·5/7/2026
Rapamycin in humans — where the evidence actually stands
PEARL trial (the first peer-reviewed RCT of intermittent rapamycin in healthy adults) found mixed results: some lean-mass and pain-improvement signals at 10mg/wk, no major safety signals at 48 weeks. Effect size was modest. We do NOT have evidence it extends human lifespan.