Educational only — not medical advice. SmartPeptide does not prescribe, diagnose, or treat. Always consult a licensed healthcare provider before using any peptide, supplement, medication, or protocol.
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Fat Loss·SmartPeptide·5/7/2026
SURMOUNT-1: tirzepatide weight-loss data summarized
SURMOUNT-1 (NEJM 2022, ~2,500 participants without diabetes) reported up to ~22.5% body-weight reduction at 72 weeks on the 15mg dose vs ~2.4% placebo. Dual GIP/GLP-1 agonism appears to outperform GLP-1-only on weight outcomes. Open questions: muscle mass preservation, long-term cardiovascular endpoints.