Thymosin Alpha-1
Immunomodulatory peptide approved in some countries (e.g., for hepatitis B). Studied in immune modulation contexts.
Educational only — not medical advice. SmartPeptide does not prescribe, diagnose, or treat. Always consult a licensed healthcare provider before using any peptide, supplement, medication, or protocol.
What the research shows
Approved in many countries (e.g., for chronic hepatitis B and as an adjunct in some immune-compromised states). Multiple clinical trials support immune-modulatory effects.
What's still experimental
Off-label uses (general immune support, COVID, oncology adjunct) have mixed and evolving evidence.
Anecdotal / community reports
Reports of fewer infections during cycles are common but not controlled.
Anecdotal reports are NOT scientific evidence. They reflect personal experience and may not generalize.
Live research
Updated hourly · sourced from PubMed + ClinicalTrials.govClinical trials (ClinicalTrials.gov)
- Thymalfasin Adjuvant Therapy in Hepatitis B Virus (HBV)-Related Hepatocellular Carcinoma (HCC) After Curative ResectionUNKNOWNNCT02281266 · PHASE4 · n=360 · 2015-01
- Efficacy of Thymosin alpha1 for Severe SepsisCOMPLETEDNCT00711620 · NA · n=366 · 2008-05
- REP 2139-Ca / Pegasys™ Combination Therapy in Hepatitis B / Hepatitis D Co-infectionCOMPLETEDNCT02233075 · PHASE2 · n=12 · 2014-09
- Platform Adaptive Embedded Trial for Acute Respiratory Distress SyndromeUNKNOWNNCT05658692 · PHASE4 · n=1000 · 2022-10-01
- TPF Concurrent Chemo-radiotherapy Plus Immunotherapy for Local Advanced Esophageal Squamous Cell CarcinomaACTIVE NOT RECRUITINGNCT06401447 · NA · n=50 · 2023-12-21
Known risks
Should only be used under licensed clinical supervision.
Reported side effects
Generally well tolerated in approved indications.
What requires medical supervision
Should only be used under licensed clinical supervision. Drug interactions and immune-modulation effects warrant monitoring.
Questions for your clinician
- Is this approved or off-label for my situation?
- What baseline immune labs should we check?
- How will we measure benefit objectively?